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Mississippi Pot Roast Slow Cooker Recipe

Course Dinner
Cuisine American
Keyword Slow Cooker
Prep Time 15 minutes
Cook Time 8 hours
Total Time 8 hours 15 minutes
Servings 6


  • 2 tablespoons mayonnaise
  • 2 teaspoons apple cider vinegar
  • 1/2 teaspoon dried dill
  • 1/4 teaspoon paprika
  • 3 pound boneless chuck roast
  • 2 teaspoons kosher salt
  • 1 1/2 teaspoons freshly ground black pepper
  • 1/4 cup all-purpose flour
  • 2 tablespoons vegetable oil
  • 3 tablespoons butter
  • 8 whole pepperoncini
  • chopped parsley for garnish


  1. In a small bowl, whisk together mayonnaise, apple cider vinegar, dried dill and paprika and set aside.

  2. Season chuck roast with salt and pepper on all sides, then sprinkle with flour making sure the entire roast is coated.

  3. In a large skillet, heat vegetable oil to almost smoking and sear roast on both sides. Transfer to slow cooker. 

  4. Add mayonnaise mixture, pepperoncini and butter to slow cooker and cook on low for about 8 hours, until roast is fork tender. Shred meat and serve.